A UNIVERSALLY APPLICABLE DIAGNOSTIC-APPROACH TO FILARIAL AND OTHER INFECTIONS

被引：53

作者：

NUTMAN, TB ^{[1
]}

ZIMMERMAN, PA ^{[1
]}

KUBOFCIK, J ^{[1
]}

KOSTYU, DD ^{[1
]}

机构：

[1] DUKE UNIV,MED CTR,DEPT IMMUNOL,DURHAM,NC 27710

来源：

PARASITOLOGY TODAY | 1994年 / 10卷 / 06期

关键词：

D O I：

10.1016/0169-4758(94)90127-9

中图分类号：

R38 [医学寄生虫学]; Q [生物科学];

学科分类号：

07 ; 0710 ; 09 ; 100103 ;

摘要：

Antibody-based assays for the diagnosis of filarial and other infections cannot reliably distinguish between past and current infection, nor con they be used to assess the efficacy of chemotherapy. In this article, Thomas Nutman, Peter Zimmerman, Joseph Kubofcik and Donna Kostyu discuss how the detection of parasite-specific PCR products using on ELISA-based assay may overcome these problems.

引用

收藏

页码：239 / 243

页数：5

相关论文

共 15 条

[1]

Ambroise-Thomas P, 1974, Acta Trop, V31, P108

[2]

INNIS MA, 1990, PCR PROTOCOLS GUIDE, P146

[3] CLONING AND CHARACTERIZATION OF A SPECIES-SPECIFIC REPETITIVE DNA-SEQUENCE FROM LOA-LOA [J].

KLION, AD ;

RAGHAVAN, N ;

BRINDLEY, PJ ;

NUTMAN, TB .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1991, 45 (02) :297-306

[4] RAPID HLA-DR OLIGOTYPING BY AN ENZYME-LINKED-IMMUNOSORBENT-ASSAY PERFORMED IN MICROTITER TRAYS [J].

KOSTYU, DD ;

PFOHL, J ;

WARD, FE ;

LEE, J ;

MURRAY, A ;

AMOS, DB .

HUMAN IMMUNOLOGY, 1993, 38 (02) :148-158

[5]

MAIZELS RM, 1990, ACT LEIDENS, V59, P261

[6] CLONING AND COMPARISON OF REPEATED DNA-SEQUENCES FROM THE HUMAN FILARIAL PARASITE BRUGIA-MALAYI AND THE ANIMAL PARASITE BRUGIA-PAHANGI [J].

MCREYNOLDS, LA ;

DESIMONE, SM ;

WILLIAMS, SA .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1986, 83 (03) :797-801

[7] ONCHOCERCA-VOLVULUS - APPLICATION OF THE POLYMERASE CHAIN-REACTION TO IDENTIFICATION AND STRAIN DIFFERENTIATION OF THE PARASITE [J].

MEREDITH, SEO ;

LANDO, G ;

GBAKIMA, AA ;

ZIMMERMAN, PA ;

UNNASCH, TR .

EXPERIMENTAL PARASITOLOGY, 1991, 73 (03) :335-344

[8] CLONING AND CHARACTERIZATION OF AN ONCHOCERCA-VOLVULUS SPECIFIC DNA-SEQUENCE [J].

MEREDITH, SEO ;

UNNASCH, TR ;

KARAM, M ;

PIESSENS, WF ;

WIRTH, DF .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1989, 36 (01) :1-10

[9] A RAPID DNA ASSAY FOR THE SPECIES-SPECIFIC DETECTION AND QUANTIFICATION OF BRUGIA IN BLOOD-SAMPLES [J].

POOLE, CB ;

WILLIAMS, SA .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1990, 40 (01) :129-136

[10]

RAMACHANDRAN CP, 1993, PARASITOL TODAY, V9, P76