ENZYMATIC-SYNTHESIS OF AMINO-ACID ESTER OF BUTYL ALPHA-D-GLUCOPYRANOSIDE

被引：2

作者：

FABRE, J

PAUL, F

MONSAN, P

BLONSKI, C

PERIE, J

机构：

[1] BIOEUROPE,F-31031 TOULOUSE,FRANCE

[2] UNIV TOULOUSE 3,CNRS,CHIM ORGAN BIOL LAB,F-31062 TOULOUSE,FRANCE

来源：

TETRAHEDRON LETTERS | 1994年 / 35卷 / 21期

关键词：

D O I：

10.1016/S0040-4039(00)73229-1

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The regiospecific enzymatic esterification of butyl alpha-D-glucopyranoside with trichloro 2,2,2 ethyl N-tBoc 4-amino butyrate was achieved using Lipozyme(R) avoiding time consuming protection-deprotection steps. The tBoc group was subsequently removed using trifluoroacetic acid, leading to the formation of butyl 6-0-(4-amino butyroyl)-alpha-D-glucopyranoside.

引用

页码：3535 / 3536

页数：2

共 7 条

[1] ENZYME CATALYZED PREPARATION OF 6-O-ACYLGLUCOPYRANOSIDES [J].