DESIGN OF ENZYME-TARGETED AGROCHEMICALS

被引：6

作者：

HAWORTH, P

SIEHL, DL

机构：

[1] Sandoz Crop Protection Corporation, Palo Alto, California 94304

来源：

JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY | 1990年 / 38卷 / 05期

关键词：

D O I：

10.1021/jf00095a026

中图分类号：

S [农业科学];

学科分类号：

09 ;

摘要：

The deliberate and considered design of chemical pesticides to inhibit specific enzyme (protein) sites represents the next likely step in the pursuit of novel agrochemicals. The transition from the current procedure of random screening, or analogue synthesis, to enzyme-targeted design will occur through positive cooperativity rather than competition. Possible strategies through which the design of enzymetargeted agrochemicals can occur are discussed. © 1990, American Chemical Society. All rights reserved.

引用

页码：1271 / 1273

页数：3

共 22 条

[1]

ARNTZEN CJ, 1983, PESTICIDE CHEM HUMAN, V3

[2]

BAILLIE AC, 1985, APPROACHES NEW LEADS

[3] CHORISMATE MUTASE INHIBITORS - SYNTHESIS AND EVALUATION OF SOME POTENTIAL TRANSITION-STATE ANALOGS [J].