EFFECT OF PH, AGITATION AND AERATION ON HYALURONIC-ACID PRODUCTION BY STREPTOCOCCUS-ZOOEPIDEMICUS

被引：84

作者：

JOHNS, MR

GOH, LT

OEGGERLI, A

机构：

[1] Department of Chemical Engineering, The University of Queensland, 4072, Queensland

来源：

BIOTECHNOLOGY LETTERS | 1994年 / 16卷 / 05期

关键词：

D O I：

10.1007/BF01023334

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

The optimum pH for both the rate of production and yield of hyaluronic acid (HA) by Streptococcus zooepidemicus from glucose medium was 6.7 +/- 0.2 under anaerobic conditions. High agitation rates (600 rpm) gave superior results compared to 300 rpm. Aeration of the culture (0.3 VVM) improved the HA yield, but not the rate of production and lead to some acetate and CO2 being formed, in addition to lactate and HA.

引用

页码：507 / 512

页数：6

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