GERMINAL-CENTERS IN T-CELL-DEPENDENT ANTIBODY-RESPONSES

被引:440
作者
LIU, YJ
JOHNSON, GD
GORDON, J
MACLENNAN, ICM
机构
[1] Yong-Jun Liu, Gerald D. Johnson, John Gordon and Ian C.M. MacLennan are at the Dept of Immunology, University of Birmingham Medical School
来源
IMMUNOLOGY TODAY | 1992年 / 13卷 / 01期
关键词
D O I
10.1016/0167-5699(92)90199-H
中图分类号
R392 [医学免疫学]; Q939.91 [免疫学];
学科分类号
100102 ;
摘要
For more than a century follicles have been recognized as a site of intense cell proliferation and cell death. At last the significance of this activity is beginning to emerge: antigen-driven B-cell proliferation, somatic mutation, positive and negative selection, and memory and plasma cell development all appear to take place within the follicle.
引用
收藏
页码:17 / 21
页数:5
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