THE MOLECULAR EPIDEMIOLOGY OF PARASITES

被引：39

作者：

HIDE, G

TAIT, A

机构：

[1] Wellcome Unit of Molecular Parasitology, University of Glasgow, Glasgow, Bearsden Road

来源：

EXPERIENTIA | 1991年 / 47卷 / 02期

基金：

英国惠康基金;

关键词：

MOLECULAR EPIDEMIOLOGY; EPIDEMIOLOGY; PARASITES; DNA PROBES; TRYPANOSOMES; LEISHMANIA; PARASITIC NEMATODES;

D O I：

10.1007/BF01945413

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

The explosion of new techniques, made available by the rapid advance in molecular biology, has provided a battery of novel approaches and technology which can be applied to more practical issues such as the epidemiology of parasites. In this review, we discuss the ways in which this new field of molecular epidemiology has contributed to and corroborated our existing knowledge of parasite epidemiology. Similar epidemiological questions can be asked about many different types of parasites and, using detailed examples such as the African trypanosomes and the Leishmania parasites, we discuss the techniques and the methodologies that have been or could be employed to solve many of these epidemiological problems.

引用

收藏

页码：128 / 142

页数：15

相关论文

共 104 条

[1] IMPROVED CHARACTERIZATION OF THEILERIA-PARVA ISOLATES USING THE POLYMERASE CHAIN-REACTION AND OLIGONUCLEOTIDE PROBES [J].

ALLSOPP, B ;

CARRINGTON, M ;

BAYLIS, H ;

SOHAL, S ;

DOLAN, T ;

IAMS, K .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1989, 35 (02) :137-147

[2] THE POTENTIAL OF USING RECOMBINANT-DNA SPECIES-SPECIFIC PROBES FOR THE IDENTIFICATION OF TROPICAL LEISHMANIA [J].

BARKER, DC ;

GIBSON, LJ ;

KENNEDY, WPK ;

NASSER, AAAA ;

WILLIAMS, RH .

PARASITOLOGY, 1986, 92 :S139-S174

[3] THE USE OF DNA PROBES IN THE IDENTIFICATION OF LEISHMANIAS - DISCRIMINATION BETWEEN ISOLATES OF THE LEISHMANIA-MEXICANA AND L-BRAZILIENSIS COMPLEXES [J].

BARKER, DC ;

BUTCHER, J .

TRANSACTIONS OF THE ROYAL SOCIETY OF TROPICAL MEDICINE AND HYGIENE, 1983, 77 (03) :285-297

[4] DNA DIAGNOSIS OF HUMAN LEISHMANIASIS [J].

BARKER, DC .

PARASITOLOGY TODAY, 1987, 3 (06) :177-184

[5]

BARKER DC, 1984, LEISHMANIA TAXONOMIE, P41

[6] 2 VARIANT SURFACE GLYCOPROTEIN GENES DISTINGUISH BETWEEN DIFFERENT SUBSTRAINS OF TRYPANOSOMA-BRUCEI-GAMBIENSE [J].

BARNES, DA ;

MOTTRAM, J ;

SELKIRK, M ;

AGABIAN, N .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1989, 34 (02) :135-146

[7] EVOLUTION OF THE GENUS LEISHMANIA AS REVEALED BY COMPARISONS OF NUCLEAR-DNA RESTRICTION FRAGMENT PATTERNS [J].

BEVERLEY, SM ;

ISMACH, RB ;

PRATT, DM .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1987, 84 (02) :484-488

[8] CHROMOSOME SIZE POLYMORPHISMS OF LEISHMANIA-DONOVANI [J].

BISHOP, RP ;

MILES, MA .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1987, 24 (03) :263-272

[9]

BLACKWELL J, 1980, NATURE, V283, P72, DOI 10.1038/283072a0

[10] QUANTITATION OF GENETIC-DIFFERENCES BETWEEN TRYPANOSOMA-BRUCEI GAMBIENSE, RHODESIENSE AND BRUCEI BY RESTRICTION ENZYME ANALYSIS OF KINETOPLAST DNA [J].

BORST, P ;

FASEFOWLER, F ;

GIBSON, WC .

MOLECULAR AND BIOCHEMICAL PARASITOLOGY, 1981, 3 (02) :117-131

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