RECOMMENDED DISTRIBUTIONS FOR EXPOSURE FACTORS FREQUENTLY USED IN HEALTH RISK ASSESSMENT

被引:114
作者
FINLEY, B [1 ]
PROCTOR, D [1 ]
SCOTT, P [1 ]
HARRINGTOIN, N [1 ]
PAUSTENBACH, D [1 ]
PRICE, P [1 ]
机构
[1] STROUDWATER CROSSING, PORTLAND, ME 04102 USA
关键词
PROBABILITY DISTRIBUTIONS; EXPOSURE FACTORS; RISK ASSESSMENT; MONTE-CARLO ANALYSIS;
D O I
10.1111/j.1539-6924.1994.tb00269.x
中图分类号
R1 [预防医学、卫生学];
学科分类号
1004 ; 120402 ;
摘要
Although there has been nearly complete agreement in the scientific community that Monte Carlo techniques represent a significant improvement in the exposure assessment process, virtually all state and federal risk assessments still rely on the traditional point estimate approach. One of the rate-determining steps to a timely implementation of Monte Carlo techniques to regulatory decision making is the development of ''standard'' data distributions that are considered applicable to any setting. For many exposure variables, there is no need to wait any longer to adopt Monte Carlo techniques into regulatory policy since there is a wealth of data from which a robust distribution can be developed and ample evidence to indicate that the variable is not significantly influenced by site-specific conditions. In this paper, we propose several distributions that can be considered standard and customary for most settings. Age-specific distributions for soil ingestion rates, inhalation rates, body weights, skin surface area, tapwater and fish consumption, residential occupancy and occupational tenure, and soil-on-skin adherence were developed. For each distribution offered in this paper, we discuss the adequacy of the database, derivation of the distribution, and applicability of the distribution to various settings and conditions.
引用
收藏
页码:533 / 551
页数:19
相关论文
共 74 条
[1]   ESTIMATING SOIL INGESTION - THE USE OF TRACER ELEMENTS IN ESTIMATING THE AMOUNT OF SOIL INGESTED BY YOUNG-CHILDREN [J].
BINDER, S ;
SOKAL, D ;
MAUGHAN, D .
ARCHIVES OF ENVIRONMENTAL HEALTH, 1986, 41 (06) :341-345
[2]   INTEGRATING UNCERTAINTY AND INTERINDIVIDUAL VARIABILITY IN ENVIRONMENTAL RISK ASSESSMENT [J].
BOGEN, KT ;
SPEAR, RC .
RISK ANALYSIS, 1987, 7 (04) :427-436
[3]   BIVARIATE DISTRIBUTIONS FOR HEIGHT AND WEIGHT OF MEN AND WOMEN IN THE UNITED-STATES [J].
BRAINARD, J ;
BURMASTER, DE .
RISK ANALYSIS, 1992, 12 (02) :267-275
[4]   HOW MUCH SOIL DO YOUNG-CHILDREN INGEST - AN EPIDEMIOLOGIC-STUDY [J].
CALABRESE, EJ ;
BARNES, R ;
STANEK, EJ ;
PASTIDES, H ;
GILBERT, CE ;
VENEMAN, P ;
WANG, X ;
LASZTITY, A ;
KOSTECKI, PT .
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1989, 10 (02) :123-137
[5]   A GUIDE TO INTERPRETING SOIL INGESTION STUDIES .2. QUALITATIVE AND QUANTITATIVE EVIDENCE OF SOIL INGESTION [J].
CALABRESE, EJ ;
STANEK, EJ .
REGULATORY TOXICOLOGY AND PHARMACOLOGY, 1991, 13 (03) :278-292
[6]  
CALABRESE EJ, 1991, PETROLEUM CONTAMINAT
[7]  
CALABRESE EJ, 1991, HYDROCARBON CONTAMIN, V1
[8]   INCREASED LEAD ABSORPTION IN INNER-CITY CHILDREN - WHERE DOES THE LEAD COME FROM [J].
CHARNEY, E ;
SAYRE, J ;
COULTER, M .
PEDIATRICS, 1980, 65 (02) :226-231
[9]  
CLAUSING P, 1987, International Archives of Occupational and Environmental Health, V59, P73, DOI 10.1007/BF00377681
[10]  
Connelly NA, 1992, EFFECTS HLTH ADVISOR