NOVEL 3-BETA-METHOXYSTEROIDS FROM THE SENEGALESE SPONGE MICROSCLERODERMA-SPIROPHORA

被引：23

作者：

COSTANTINO, V

FATTORUSSO, E

MANGONI, A

AKNIN, M

GAYDOU, EM

机构：

[1] UNIV NAPLES,DIPARTIMENTO CHIM SOSTANZE NAT,I-80131 NAPLES,ITALY

[2] UNIV LA REUNION,CHEM ORGAN LAB,ST DENIS,FRANCE

[3] FAC SCI & TECH ST JEROME,PHYTOCHIM MARSEILLE LAB,MARSEILLE,FRANCE

来源：

STEROIDS | 1994年 / 59卷 / 03期

关键词：

(24S)-24-ETHYL-3-BETA-METHOXY-8-ALPHA,9-ALPHA-OXIDO-8,9-SECO-5-ALPHA-CHOLESTA-7,9(11)-DIENE; (24S)-24-ETHYL-3-BETA-METHOXY-8-ALPHA,9-ALPHA-OXIDO-8,9-SECO,5-ALPHA-CHOLESTA-7,8(14)-DIENE; (24S)-24-ETHYL-3-BETA-METHOXY-8-ALPHA; 9-ALPHA-EPOXY-5-ALPHA-CHOLEST-14-ENE; SPONGES; STEROLS; 3-O-METHYL; 3-BETA-METHOXYSTEROIDS; MICROSCLERODERMA SPIROPHORA;

D O I：

10.1016/0039-128X(94)90025-6

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

The Senegalese sponge Microscleroderma spirophora has been found to produce exclusively very unusual 3 beta-methoxysteroids in place of the common 3 beta-hydroxysteroids. Six different methoxysteroids (three of which are novel compounds) have been isolated and identified by spectroscopic means (MS, IR H-1 and C-13 NMR), and their taxonomic significance discussed. A new method for the determination of the configuration at C-24 in satuiated 24-ethyl side chains is also proposed.

引用

页码：181 / 184

页数：4

共 8 条

[1] SENSITIVITY-ENHANCED TWO-DIMENSIONAL HETERONUCLEAR SHIFT CORRELATION NMR-SPECTROSCOPY [J].