ATYPICAL VARICELLA EXANTHEMA ASSOCIATED WITH SKIN INJURY

被引:23
作者
BELHORN, TH [1 ]
LUCKY, AW [1 ]
机构
[1] CHILDRENS HOSP,MED CTR,DIV PEDIAT DERMATOL,ELLAND & BETHESDA AVE,CINCINNATI,OH 45229
关键词
D O I
10.1111/j.1525-1470.1994.tb00566.x
中图分类号
R75 [皮肤病学与性病学];
学科分类号
100206 [皮肤病与性病学];
摘要
Varicella is a common childhood disease with a typical exanthem. We present four children with severe, localized disease, all associated with some form of trauma to the skin during the incubation period: a 3 1/2-year-old boy sustained wasp stings on the hand, a 5-year-old boy received extensive sun exposure, a neonate had iatrogenic trauma to her arm, and a 13-year-old boy underwent knee arthroscopy and was wearing a cast. It is postulated that such injuries to the skin either allowed more virus-infected cells to enter the skin at the sites, or that factors such as insect venom and ultraviolet light altered local immunity to varicella zoster virus.
引用
收藏
页码:129 / 132
页数:4
相关论文
共 10 条
[1]
Belhorn TH, Myers MG., Varicella (chickenpox), Conn's current therapy, (1993)
[2]
Tyring SK., Natural history of varicella zoster virus, Semin Dermatol, 11, 3, pp. 211-217, (1992)
[3]
Reisman RE., Insect allergy, Allergy principles and practice, (1988)
[4]
Mauriello PM, Barde SH, Georgitis JW, Reisman RE., Natural history of large local reactions from stinging insects, J Allergy Clin Immunol, 74, 4, pp. 494-498, (1984)
[5]
Case RL, Altman LC, VanArsdel PP, Role of cellmediated immunity in Hymenoptera allergy, J Allergy Clin Immunol, 68, 5, pp. 399-405, (1981)
[6]
Gilchrest B, Baden HP., Photodistribution of viral exanthems, Pediatrics, 54, 2, pp. 136-138, (1974)
[7]
Boyd AS, Nelder KH, Zemtsov A, Shihada B., Photolocalized varicella, J Am Acad Dermatol, 26, 5, pp. 772-774, (1992)
[8]
Baadsgaard O., In vivo ultraviolet irradiation of human skin results in profound perturbation of the immune system, Arch Dermatol, 127, pp. 99-109, (1992)
[9]
The use of oral acyclovir in otherwise healthy children with varicella, Pediatrics, 91, 3, pp. 674-676, (1993)
[10]
Dunkle LM, Arvin AM, Whitley RJ, Et al., A controlled trial of acyclovir for chickenpox in normal children, N Engl J Med, 325, 22, pp. 1539-1544, (1991)