SYNTHESIS OF UDP-6-DEOXY-D-GALACTOSES AND UDP-6-FLUORO-D-GALACTOSES AND THEIR ENZYMATIC GLYCOSYL TRANSFER TO MONOANTENNARY AND BIANTENNARY CARBOHYDRATE CHAINS

被引:28
作者
KODAMA, H [1 ]
KAJIHARA, Y [1 ]
ENDO, T [1 ]
HASHIMOTO, H [1 ]
机构
[1] TOKYO INST TECHNOL,DEPT LIFE SCI,MIDORI KU,YOKOHAMA,KANAGAWA 227,JAPAN
关键词
D O I
10.1016/0040-4039(93)85060-A
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
Glycosylation with chemicallY prepared UDP-6-deoxy-D-galactose and its 6-fluoro analog using bovine (1-4)-beta-D-galactosyltransferase was demonstrated to be effective enough for practical purpose. A biantennary pentasaccharide having two 6'-deoxylactosamine residues was synthesized.
引用
收藏
页码:6419 / 6422
页数:4
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