THE EVOLUTION OF INHALER TECHNOLOGY

被引：63

作者：

GROSSMAN, J ^{[1
]}

机构：

[1] ALBANY MED COLL,ALBANY,NY

来源：

JOURNAL OF ASTHMA | 1994年 / 31卷 / 01期

关键词：

D O I：

10.3109/02770909409056770

中图分类号：

R392 [医学免疫学];

学科分类号：

100102 ;

摘要：

Historically, the evolution of inhalation therapy can be traced to India 4000 years ago. The antecedents of contemporary inhalation therapy, however, began in the nineteenth-century industrial age with the invention of the glass bulb nebulizer. From there, inhaler technology evolved along two pathways characterized by refinements in existent nebulizer technology and the invention of a portable inhalation device, the metered-dose inhaler (MDI). More recently, growing recognition of problems associated with MDI use (chiefly, its reliance on coordinated patient inhalation and actuation technique) led to modifications in the MDI itself with auxiliary devices (spacers) and the development of new inhaler systems-dry powdered inhalers (DPIs) and the breath-actuated metered-dose inhaler (BAI-MDI).

引用

页码：55 / 64

页数：10

共 20 条

[1]

Lane D.J., Storr A., Bronchodilators, Asthma: The Facts2nd ed, pp. 126-140, (1987)

[2]

McPherson S.P., Respiratory Therapy Equipment, (1985)

[3]

Tinkelman D.G., Berkowitz R.B., Cole W.Q., Review article: Aerosols in the treatment of asthma, J Asthma, 28, 4, pp. 243-249, (1991)

[4]

Jones M.D., Yeager H., Inhaler and spacer use in obstructive airway diseases, Am Family Physician, 42, 4, pp. 1007-1013, (1990)

[5]

Berenberg M.J., Baigelman W., Cupples L.A., Pearce L., Comparison of metered-dose inhaler attached to an aerochamber with an updraft nebulizer for the administration of metaproterenol in hospitalized patients, J Asthma, 22, 2, pp. 87-92, (1985)

[6]

Summer W.K., Elson R., Thorpe L., Nelson S., Haponik E.F., Aerosol bronchodilator delivery methods: Relative impact on pulmonary function and cost of respiratory care, Arch Intern Med, 149, pp. 618-623, (1989)

[7]

Berry R.B., Shinto R.A., Wong F.H., Despars J.A., Light R.W., Nebulizer vs spacer for bronchodilator delivery in patients hospitalized for acute exacerbations of COPD, Chest, 96, 6, pp. 1241-1246, (1989)

[8]

O'Reilly J.F., Gould G., Kendrick A.H., Laszlo G., Domiciliary comparison of terbutaline treatment by metered dose inhaler with and without conical spacer in moderately severe chronic asthma, Thorax, 41, pp. 766-770, (1986)

[9]

Newman S.P., Aerosol physiology, deposition, and metered dose inhalers, Allergy Proc, 12, 1, pp. 42-45, (1991)

[10]

Costello J., MDI: What may be the consequences of incorrect usage?, Med Dialogue Weekly, 197, (1988)

← 1 2 →