COMPARISON OF MASS-SPECTROMETRIC METHODS FOR TRACE LEVEL SCREENING OF HEXACHLOROBENZENE AND TRICHLOROPHENOL IN HUMAN-BLOOD SERUM AND URINE

被引：35

作者：

YOST, RA

FETTEROLF, DD

HASS, JR

HARVAN, DJ

WESTON, AF

SKOTNICKI, PA

SIMON, NM

机构：

[1] NIEHS,NATL TOXICOL PROGRAM,MOLEC BIOPHYS LAB,RES TRIANGLE PK,NC 27709

[2] OCCIDENTAL CHEM CORP,RES CTR,GRAND ISL,NY 14072

来源：

ANALYTICAL CHEMISTRY | 1984年 / 56卷 / 12期

关键词：

Spectroscopic analysis;

D O I：

10.1021/ac00276a054

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

The combination of more selective mass spectrometric techniques (high-resolution mass spectrometry and tandem mass spectrometry - both triple quadrupole MS/MS and MIKES) with short retention time gas chromatography is compared with conventional capillary GC/MS for the screening of human serum and urine for hexachlorobenzene and trichlorophenol. The various techniques are evaluated in terms of detection limits, ability to obtain zero blanks, reproducibility, linearity, and speed of analysis. GC/MS/MS makes possible screening at sub-part-per-billion levels 20 times more rapidly than by HRGC/MS.

引用

页码：2223 / 2228

页数：6

共 10 条

[1] CHEMICAL-ANALYSIS OF HUMAN-BLOOD FOR ASSESSMENT OF ENVIRONMENTAL EXPOSURE TO SEMIVOLATILE ORGANOCHLORINE CHEMICAL CONTAMINANTS [J].