C-ERBB-3 PROTEIN EXPRESSION IN HUMAN BREAST-CANCER - COMPARISON WITH OTHER TUMOR VARIABLES AND SURVIVAL

被引：71

作者：

QUINN, CM ^{[1
]}

OSTROWSKI, TL ^{[1
]}

LANE, SA ^{[1
]}

LONEY, DP ^{[1
]}

TEASDALE, J ^{[1
]}

BENSON, EA ^{[1
]}

机构：

[1] GEN INFIRM,DEPT SURG,LEEDS,W YORKSHIRE,ENGLAND

来源：

HISTOPATHOLOGY | 1994年 / 25卷 / 03期

关键词：

C-ERBB-3; MONOCLONAL ANTIBODY RTJ1; MALIGNANT BREAST TUMORS;

D O I：

10.1111/j.1365-2559.1994.tb01324.x

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

c-erbB-3 protein expression was investigated immunohistochemically in a series of 97 malignant breast tumours using the monoclonal antibody RTJ1. Twenty-eight cases (28.8%) showed c-erbB-3 overexpression, 31 cases (32%) showed normal levels of c-erbB-3 and 38 cases (39.2%) were c-erbB-3 negative, c-erbB-3 overexpression was positively but not significantly related to negative lymph node status and survival over a l0-year follow-up period.

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收藏

页码：247 / 252

页数：6

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