IMMUNOLOGICAL STUDIES ON OPPORTUNISTIC INFECTION AND THE DEVELOPMENT OF ADULT T-CELL LEUKEMIA

被引:26
作者
TASHIRO, T
YAMASAKI, T
NAGAI, H
KIKUCHI, H
NASU, M
机构
[1] Second Department of Internal Medicinc, Oita Medical University, Oita
[2] Second Department of Internal Medicine, Oita Medical University, Hasama-machi
关键词
SMOLDERING ATL; HTLV-I CARRIER; CRYPTOCOCCOSIS; PNEUMOCYSTIS-CARINII PNEUMONIA;
D O I
10.2169/internalmedicine.31.1132
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Three patients with opportunistic infection preceding adult T-cell leukemia (ATL) are presented: a 66-year-old woman with cryptococcosis and Pneumocystis carinii pneumonia, a 46-year-old man with Pneumocystis carinii pneumonia, and a 55-year-old woman with cryptococcosis. Although, at the first examination, the first two had smoldering type ATL and the third case was an HTLV-I carrier, all three developed overt ATL 14-16 months after the onset of opportunistic infection. It is considered that there is immune suppression already present in HTLV-I carriers and in patients with smoldering ATL, and opportunistic infection is predictive of the development of ATL.
引用
收藏
页码:1132 / 1136
页数:5
相关论文
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