2,4-DIAMINO-6,7-DIMETHOXYQUINAZOLINES .1. 2-[4-(1,4-BENZODIOXAN-2-YLCARBONYL)PIPERAZIN-1-YL] DERIVATIVES AS ALPHA-1-ADRENOCEPTOR ANTAGONISTS AND ANTIHYPERTENSIVE AGENTS

被引：131

作者：

CAMPBELL, SF ^{[1
]}

DAVEY, MJ ^{[1
]}

HARDSTONE, JD ^{[1
]}

LEWIS, BN ^{[1
]}

PALMER, MJ ^{[1
]}

机构：

[1] PFIZER LTD,CENT RES,DEPT DISCOVERY BIOL,SANDWICH,KENT,ENGLAND

来源：

关键词：

D O I：

10.1021/jm00384a009

中图分类号：

R914 [药物化学];

学科分类号：

100701 ;

摘要：

引用

页码：49 / 57

页数：9

共 35 条

[1] [Anonymous], 1985, Hypertension, V7, P641
[2] QUANTITATIVE PROTON AFFINITIES, IONIZATION-POTENTIALS, AND HYDROGEN AFFINITIES OF ALKYLAMINES
AUE, DH
WEBB, HM
BOWERS, MT
[J]. JOURNAL OF THE AMERICAN CHEMICAL SOCIETY, 1976, 98 (02) : 311 - 317
[3] AUGSTEIN J, 1965, J MED CHEM, V8, P446
[4] PYRIMIDINE REACTIONS .7. METHYLATION OF SUBSTITUTED 2,4-DIAMINOPYRIMIDINES
BROWN, DJ
TEITEI, T
[J]. JOURNAL OF THE CHEMICAL SOCIETY, 1965, (JAN): : 755 - &
[5] BUHLER FR, 1982, J CARDIOVASC PHARM, V4, pS134
[6] Campbell S F, 1986, Drug Des Deliv, V1, P83
[7] CAMPBELL SA, UNPUB
[8] CAMPBELL SF, 1984, XRAY CRYSTALLOGRAPHY, P347
[9] CAMPBELL SF, 1984, 2ND SCI RSC MED CHEM, P18
[10] CAMPBELL SF, Patent No. 2007656