Molecular cloning and expression of alpha parvalbumin in the guinea pig cochlea

被引：18

作者：

SotoPrior, A ^{[1
]}

Cluzel, M ^{[1
]}

Renard, N ^{[1
]}

Ripoll, C ^{[1
]}

LavigneRebillard, M ^{[1
]}

Eybalin, M ^{[1
]}

Hamel, CP ^{[1
]}

机构：

[1] UNIV MONTPELLIER 1,CHU,HOP ST CHARLES,F-34295 MONTPELLIER 05,FRANCE

来源：

MOLECULAR BRAIN RESEARCH | 1995年 / 34卷 / 02期

关键词：

alpha parvalbumin; RT-PCR; in situ hybridization; immunohistochemistry; cochlea; guinea pig;

D O I：

10.1016/0169-328X(95)00205-7

中图分类号：

Q189 [神经科学];

学科分类号：

071006 ;

摘要：

We have cloned and sequenced an alpha parvalbumin cDNA from the guinea pig cochlea. The deduced amino acid sequence shows greater identity with the rabbit sequence (86.3%) than with other mammalian sequences (< 82%). Using in situ hybridization and immunohistochemistry, alpha parvalbumin mRNA and protein were found in primary auditory neurons and inner hair cells, in agreement with RT-PCR data showing alpha parvalbumin mRNA expression in the spiral ganglion and the organ of Corti.

引用

页码：337 / 342

页数：6

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