CHROMOSOME-ABNORMALITIES IN HUMAN CANCER AND LEUKEMIA

被引：65

作者：

SANDBERG, AA

机构：

[1] Southwest Biomedical Research Institute, Scottsdale

来源：

MUTATION RESEARCH | 1991年 / 247卷 / 02期

关键词：

CHROMOSOME ABERRATION; CANCER; LEUKEMIA;

D O I：

10.1016/0027-5107(91)90019-K

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

The meaning and application of chromosomal (cytogenetic, karyotypic) changes in human leukemia and cancer have been succinctly reviewed in this article. Thus, the usefulness of these changes in the diagnosis, classification and prognosis of various leukemic conditions and, more recently, of solid tumors is stressed and their application to molecular studies indicated. The meaning of primary (specific) and additional (secondary) karyotypic changes in malignant and benign tumors is discussed. Tables containing the common cytogenetic changes in leukemias and tumors, including benign ones, are included.

引用

页码：231 / 240

页数：10

共 13 条

[1]

GIBAS LM, 1984, KARYOGRAM, V10, P25

[2] RECURRENT CHROMOSOME TRANSLOCATIONS IN LIPOSARCOMA [J].