USE OF MONOCLONAL-ANTIBODIES IN HUMAN TRANSPLANTATION

被引：17

作者：

DANTAL, J ^{[1
]}

SOULILLOU, JP ^{[1
]}

机构：

[1] INSERM,CLIN IMMUNOL & RES UNIT,NANTES,FRANCE

来源：

CURRENT OPINION IN IMMUNOLOGY | 1991年 / 3卷 / 05期

关键词：

D O I：

10.1016/0952-7915(91)90106-B

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Monoclonal antibodies are of growing importance in human organ transplantation in the prophylactic and curative treatment of cellular rejection. Among the pan T-lymphocyte monoclonal antibodies, OKT3 has been much studied, although clinical research is engaged with more selective targets of allorecognition and/or their consequences, for example monoclonal antibodies directed against the interleukin-2 receptor, adhesion molecules and CD4 molecules. We summarize the use of these monoclonal antibodies and bioreagents in clinical transplantation.

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页码：740 / 747

页数：8

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