NEUROSCIENCE RESEARCH - HOW HAS IT CONTRIBUTED TO OUR UNDERSTANDING OF ALCOHOL-ABUSE AND ALCOHOLISM - A REVIEW

被引:65
作者
HUNT, WA
机构
[1] Neurosciences and Behavioral Research Branch, National Institute on Alcohol Abuse and Alcoholism, Rockville, Maryland
关键词
MEMBRANES; ION CHANNELS; NEUROTRANSMITTERS; 2ND MESSENGERS; BRAIN DAMAGE;
D O I
10.1111/j.1530-0277.1993.tb05664.x
中图分类号
R194 [卫生标准、卫生检查、医药管理];
学科分类号
摘要
Alcohol abuse and alcoholism are the greatest substance abuse problems in the United States today and contribute to numerous medical and social problems. To deal with many of these problems, an understanding of how alcohol acts on the brain is extremely important. Advances in neuroscience research have provided significant clues about where and how alcohol works on the brain. Alcohol clearly acts on membrane function, altering such processes as ion movements and neurotransmitter interactions with their receptors. Although these alcohol-induced alterations are presumed to relate to changes in behavior, this has not been clearly established. However, alcohol research is on the threshold of making a giant leap forward in our understanding the etiology of alcoholism.
引用
收藏
页码:1055 / 1065
页数:11
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