PROTECTIVE EFFECT OF REDUCED GLUTATHIONE AGAINST CISPLATIN-INDUCED RENAL AND SYSTEMIC TOXICITY AND ITS INFLUENCE ON THE THERAPEUTIC ACTIVITY OF THE ANTITUMOR DRUG

被引：161

作者：

ZUNINO, F ^{[1
]}

PRATESI, G ^{[1
]}

MICHELONI, A ^{[1
]}

CAVALLETTI, E ^{[1
]}

SALA, F ^{[1
]}

TOFANETTI, O ^{[1
]}

机构：

[1] BOEHRINGER BIOCHEM ROBIN,DIV FARMACOL,MILAN,ITALY

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1989年 / 70卷 / 1-2期

关键词：

D O I：

10.1016/0009-2797(89)90065-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：89 / 101

页数：13

共 35 条

[1] SOME PROCEDURES TO REDUCE CIS-PLATINUM TOXICITY REDUCE ANTITUMOUR ACTIVITY [J].

AAMDAL, S ;

FODSTAD, O ;

PIHL, A .

CANCER TREATMENT REVIEWS, 1987, 14 (3-4) :389-395

[2] PHARMACOKINETICS OF INTRAVENOUSLY ADMINISTERED GLUTATHIONE IN THE RAT [J].

AMMON, HPT ;

MELIEN, MCM ;

VERSPOHL, EJ .

JOURNAL OF PHARMACY AND PHARMACOLOGY, 1986, 38 (10) :721-725

[3]

ANDREWS PA, 1985, CANCER RES, V45, P6250

[4]

BODENNER DL, 1986, CANCER RES, V46, P2751

[5]

BOHM S, 1988, PLATINUM OTHER METAL, P456

[6]

BORCH RF, 1988, ORGAN DIRECTED TOXIC, P190

[7]

CONNORS T. A., 1966, EUR J CANCER, V2, P293, DOI 10.1016/0014-2964(66)90042-9

[8] REACTION OF PLATINUM(II) ANTITUMOR AGENTS WITH SULFHYDRAL COMPOUNDS AND THE IMPLICATIONS FOR NEPHROTOXICITY [J].

CORDEN, BJ .

INORGANICA CHIMICA ACTA-BIOINORGANIC CHEMISTRY, 1987, 137 (1-2) :125-130

[9] TISSUE SULFHYDRYL GROUPS [J].

ELLMAN, GL .

ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS, 1959, 82 (01) :70-77

[10]

GERAN RI, 1972, CANC CHEMOTHER REP, V3, P1

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