PROTECTIVE EFFECT OF REDUCED GLUTATHIONE AGAINST CISPLATIN-INDUCED RENAL AND SYSTEMIC TOXICITY AND ITS INFLUENCE ON THE THERAPEUTIC ACTIVITY OF THE ANTITUMOR DRUG

被引：161

作者：

ZUNINO, F ^{[1
]}

PRATESI, G ^{[1
]}

MICHELONI, A ^{[1
]}

CAVALLETTI, E ^{[1
]}

SALA, F ^{[1
]}

TOFANETTI, O ^{[1
]}

机构：

[1] BOEHRINGER BIOCHEM ROBIN,DIV FARMACOL,MILAN,ITALY

来源：

CHEMICO-BIOLOGICAL INTERACTIONS | 1989年 / 70卷 / 1-2期

关键词：

D O I：

10.1016/0009-2797(89)90065-3

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

引用

页码：89 / 101

页数：13

共 35 条

[21] THE MULTIPLE ROLES OF GLUTATHIONE IN DRUG-METABOLISM [J].

ORRENIUS, S ;

MOLDEUS, P .

TRENDS IN PHARMACOLOGICAL SCIENCES, 1984, 5 (10) :432-435

[22]

ORRENIUS S, 1983, FED PROC, V42, P3177

[23]

OZOLS RF, 1985, SEMIN ONCOL, V12, P21

[24]

PRATESI G, 1985, CANCER TREAT REP, V69, P219

[25]

ROBERTS JJ, 1984, CANCER CHEMOTHER ANN, V6, P118

[26]

ROSE WC, 1986, ANTICANCER RES, V6, P557

[27] THE MOUSE AS A MODEL FOR PREDICTING THE MYELOSUPPRESSIVE EFFECTS OF ANTICANCER DRUGS [J].

SCHURIG, JE ;

FLORCZYK, AP ;

BRADNER, WT .

CANCER CHEMOTHERAPY AND PHARMACOLOGY, 1986, 16 (03) :243-246

[28]

SCHURIG JE, 1980, CISPLATIN CURRENT ST, P227

[29] HEMATOLOGICAL TOXICITY OF CARBOPLATIN IN RATS [J].

SIDDIK, ZH ;

BOXALL, FE ;

HARRAP, KR .

BRITISH JOURNAL OF CANCER, 1987, 55 (04) :375-379

[30] AN INVITRO STUDY COMPARING THE CYTO-TOXICITY OF 3 PLATINUM COMPLEXES WITH REGARD TO THE EFFECT OF THIOL DEPLETION [J].

SMITH, E ;

BROCK, AP .

BRITISH JOURNAL OF CANCER, 1988, 57 (06) :548-552

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