SUBSTITUTION-REACTIONS OF A NUCLEOFUGAL GROUP IN HEPTAMETHINE CYANINE DYES - SYNTHESIS OF AN ISOTHIOCYANATO DERIVATIVE FOR LABELING OF PROTEINS WITH A NEAR-INFRARED CHROMOPHORE

被引：166

作者：

STREKOWSKI, L

LIPOWSKA, M

PATONAY, G

机构：

来源：

JOURNAL OF ORGANIC CHEMISTRY | 1992年 / 57卷 / 17期

关键词：

D O I：

10.1021/jo00043a009

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

The reactions of dye 1 with MeONa, MeNH2, PhONa, PhSNa, PhSH, and 4-H2NPhSH to yield the corresponding derivatives 2a-e, hydrodechlorination of 1 to 3 in the presence of EtSNa or PhSNa/Ph2PH, and synthesis of the SCN-substituted dye 4, a new reagent for ultratrace detection of proteins, are described.

引用

页码：4578 / 4580

页数：3

共 16 条

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