LIPASE-CATALYZED TRANSESTERIFICATION IN THE PREPARATION OF OPTICALLY-ACTIVE SOLKETAL

被引：19

作者：

VANTTINEN, E

KANERVA, LT

机构：

[1] UNIV TURKU,DEPT CHEM,SF-20500 TURKU,FINLAND

[2] UNIV TURKU,DEPT BIOMED,SF-20500 TURKU,FINLAND

来源：

JOURNAL OF THE CHEMICAL SOCIETY-PERKIN TRANSACTIONS 1 | 1994年 / 23期

关键词：

D O I：

10.1039/p19940003459

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

A lipase-catalysed method for a large-scale preparation of both (R)- (ee 99%) and (S)-solketal (ee 94% after double resolution) has been described. Separation of the reaction products in the resolution mixture was achieved by extraction/distillation and the unwanted enantiomer was racemized and recycled.

引用

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页码：3459 / 3463

页数：5

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