PHARMACOLOGICAL PROPHYLAXIS AGAINST POSTOPERATIVE GRAFT OCCLUSION AFTER PERIPHERAL VASCULAR-SURGERY - A WORLDWIDE SURVEY

被引:17
作者
LINDBLAD, B
WAKEFIELD, TW
STANLEY, TJ
BERGQVIST, D
NICHOL, BJ
GREENFIELD, LJ
STANLEY, JC
BERGENTZ, SE
机构
[1] Department of Surgery, Lund University, Malmö General Hospital, Malmö
[2] Section of Vascular Surgery, Department of Surgery, University of Michigan Medical Center, Ann Arbor, MI
[3] Department of Surgery, University Hospital, Uppsala
关键词
PHARMACOLOGICAL PROPHYLAXIS; VASCULAR RECONSTRUCTIONS; ASA; ANTICOAGULATION;
D O I
10.1016/S1078-5884(05)80129-7
中图分类号
R61 [外科手术学];
学科分类号
摘要
Objectives: To define current practice regarding the use of pharmacological prophylaxis to prevent postoperative graft occlusion. Design: Prospective open questionnaire. Materials and Methods: Questionnaires regarding this subject were sent to vascular surgeons throughout the world to analyse current practice. Results: 651 questionnaires were returned with a response rate of 62% and form the basis for this report. Data from 100334 vascular reconstructions were reported in this survey. Prophylaxis against postoperative graft occlusions was common. Treatment periods were usually greater than 1 year. Among carotid surgery patients, 82% received prophylaxis, consisting mainly of low-dose acetysalicylic acid (ASA). In Mid-Europe the use of oral anticoagulation was more common than in other regions (p < 0.001). Among aneurysm surgery patients, 38% received prophylaxis. For infrainguinal bypass, ASA in low dose was the most commonly used agent worldwide. However, oral anticoagulation was mole frequent in Mid-Europe, in contrast to South America where the combination of ASA and dipyridamole was most common. Considerable geographical differences regarding patient selection, the frequency of specific procedures and operative techniques existed. Conclusions: Important world-wide differences exist regarding prophylaxis for postoperative graft occlusion.
引用
收藏
页码:267 / 271
页数:5
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