OBSTETRICAL ADVANTAGES AND PERINATAL RISKS OF INDOMETHACIN - A REPORT OF 818 CASES

被引：18

作者：

MARPEAU, L

BOUILLIE, J

BARRAT, J

MILLIEZ, J

机构：

[1] Clinique de gynécologie obstétrique, Service du Professeur J. Milliez, CHU St. Antoine, Paris

来源：

FETAL DIAGNOSIS AND THERAPY | 1994年 / 9卷 / 02期

关键词：

INDOMETHACIN; PREMATURITY; PERSISTENT FETAL CIRCULATION; OLIGO/ANURIA; PNEUMOTHORAX;

D O I：

10.1159/000263917

中图分类号：

R71 [妇产科学];

学科分类号：

100211 ;

摘要：

In a series of 818 patients treated with indomethacin during pregnancy, the rate of perinatal complications was 1.8%. The risk was increased to 13% if indomethacin was being taken at the time of delivery, and when treatment was prolonged. The serious nature of certain complications (persistence of fetal circulation and oligo/anuria) means that indomethacin should only be used in cases in which betamimetic drugs are formally contraindicated or if there is a risk of unacceptable prematurity. Even in such cases, indomethacin should only be given for short period (<1 week).

引用

页码：110 / 115

页数：6

共 14 条

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