NEW APPROACH TO SCREENING DRUGS FOR ACTIVITY AGAINST AFRICAN TRYPANOSOMES

被引：79

作者：

FAIRLAMB, AH ^{[1
]}

OPPERDOES, FR ^{[1
]}

BORST, P ^{[1
]}

机构：

[1] UNIV AMSTERDAM,BIOCHEM LAB,MED ENZYMOL & MOLEC BIOL SECT,AMSTERDAM 1004,NETHERLANDS

来源：

关键词：

D O I：

10.1038/265270a0

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

引用

页码：270 / 271

页数：2

共 14 条

[1] RELATION BETWEEN BLOOD-LEVEL OF A SUBSTRATE AND ENZYME-KINETICS STUDIED WITH GLYCEROL IN RAT
ACKERMANN, RH
BASSLER, KH
WAGNER, K
[J]. HOPPE-SEYLERS ZEITSCHRIFT FUR PHYSIOLOGISCHE CHEMIE, 1974, 355 (05): : 576 - 582
[2] Bowman I.B.R., 1976, P501
[3] BOWMAN IBR, 1976, BIOLOGY KINETOPLASTI, V1, P435
[4] TRYPANOSOMIASIS - APPROACH TO CHEMOTHERAPY BY INHIBITION OF CARBOHYDRATE CATABOLISM
CLARKSON, AB
BROHN, FH
[J]. SCIENCE, 1976, 194 (4261) : 204 - 206
[5] BLOOD PLATELETS AS A SOURCE OF ENZYME ACTIVITY IN WASHED TRYPANOSOME SUSPENSIONS
DIXON, H
[J]. NATURE, 1966, 210 (5034) : 428 - &
[6] FULTON J. D., 1959, EXPTL PARASITOL, V8, P137, DOI 10.1016/0014-4894(59)90014-1
[7] PROPERTIES OF L-ALPHA-GLYCEROPHOSPHATE OXIDASE AND ITS ROLE IN THE RESPIRATION OF TRYPANOSOMA-RHODESIENSE
GRANT, PT
SARGENT, JR
[J]. BIOCHEMICAL JOURNAL, 1960, 76 : 229 - 237
[8] Newton B. A., 1974, Trypanosomiasis and leishmaniasis. Ciba Foundation Symposium No.20., P285
[9] Opperdoes F.R., 1976, P509
[10] POTENTIAL USE OF INHIBITORS OF GLYCEROL-3-PHOSPHATE OXIDASE FOR CHEMOTHERAPY OF AFRICAN TRYPANOSOMIASIS
OPPERDOES, FR
BORST, P
FONCK, K
[J]. FEBS LETTERS, 1976, 62 (02) : 169 - 172