CHEMICAL MODIFICATION OF TYLOSIN - SYNTHESIS OF AMINO DERIVATIVES AT C-20 POSITION OF TYLOSIN AND DEMYCAROSYLTYLOSIN

被引：15

作者：

MATSUBARA, H ^{[1
]}

INOKOSHI, J ^{[1
]}

NAKAGAWA, A ^{[1
]}

TANAKA, H ^{[1
]}

OMURA, S ^{[1
]}

机构：

[1] KITASATO INST,MINATO KU,TOKYO 108,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1983年 / 36卷 / 12期

关键词：

D O I：

10.7164/antibiotics.36.1713

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：1713 / 1721

页数：9

共 12 条

[1]

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[2]

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[3] PHYSICOCHEMICAL PROPERTIES OF NEW ACYL DERIVATIVES OF TYLOSIN PRODUCED BY MICROBIAL TRANSFORMATION [J].

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[4] BIOLOGICAL PROPERTIES OF NEW ACYL DERIVATIVES OF TYLOSIN [J].

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[5] ACTIVITY OF 4''-ACYLATED TYLOSIN DERIVATIVES AGAINST MACROLIDE-RESISTANT GRAM-POSITIVE BACTERIA [J].

OKAMOTO, R ;

NOMURA, H ;

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[6] NOVEL DIMERIC DERIVATIVES OF LEUCOMYCINS AND TYLOSIN, 16-MEMBERED MACROLIDES [J].

OMURA, S ;

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JOURNAL OF MEDICINAL CHEMISTRY, 1982, 25 (03) :271-275

[7] RIBOSOME-BINDING ACTIVITIES AND ANTI-MICROBIAL ACTIVITIES OF TYLOSIN AND ITS RELATED-COMPOUNDS [J].

OMURA, S ;

INOKOSHI, J ;

MATSUBARA, H ;

TANAKA, H .

JOURNAL OF ANTIBIOTICS, 1983, 36 (12) :1709-1712

[8] STRUCTURE-ACTIVITY-RELATIONSHIPS AMONG O-ACYL DERIVATIVES OF LEUCOMYCIN - CORRELATION OF MINIMAL INHIBITORY CONCENTRATIONS WITH BINDING TO ESCHERICHIA-COLI RIBOSOMES [J].

OMURA, S ;

NAKAGAWA, A ;

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PESTKA, S .

JOURNAL OF MEDICINAL CHEMISTRY, 1977, 20 (05) :732-736

[9] BINDING OF [H-3]TETRAHYDROLEUCOMYCIN A3 TO ESCHERICHIA-COLI RIBOSOMES AND THE EFFECT OF 3''-O-ACYL DERIVATIVES OF LEUCOMYCINS ON THE BINDING [J].

OMURA, S ;

TANAKA, H ;

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[10]

OMURA S, 1979, HAKKO TO KOGYO, V37, P1171

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