SEPARATION OF BETA-CAROTENE MIXTURES PRECIPITATED FROM LIQUID SOLVENTS WITH HIGH-PRESSURE CO2

被引：53

作者：

CHANG, CMJ ^{[1
]}

RANDOLPH, AD ^{[1
]}

CRAFT, NE ^{[1
]}

机构：

[1] UNIV ARIZONA,DEPT CHEM ENGN,TUCSON,AZ 85721

来源：

BIOTECHNOLOGY PROGRESS | 1991年 / 7卷 / 03期

关键词：

D O I：

10.1021/bp00009a011

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

Solids precipitation from liquid solvents, with dissolution by high-pressure CO2 as an antisolvent to create supersaturation, is a potentially attractive crystallization process. Solids can be recrystallized and easily isolated from the liquid solvent. The gas antisolvent solvent (GAS) process was used to separate and purify beta-carotene from a mixture containing carotene oxidation products. Total beta-carotene was successfully separated from oxides, and an enriched trans-beta-carotene was obtained from its cis isomers. The separation was carried out in both batch and continuous modes. Relative solubility of the analytes and the antisolvent (CO2) have a dramatic influence on the absolute yield and purity of the product.

引用

页码：275 / 278

页数：4

共 9 条

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