POSITIVELY CHARGED RESIDUES ARE IMPORTANT DETERMINANTS OF MEMBRANE-PROTEIN TOPOLOGY

被引：119

作者：

DALBEY, RE

机构：

[1] Department of Chemistry, The Ohio State University, Columbus

来源：

TRENDS IN BIOCHEMICAL SCIENCES | 1990年 / 15卷 / 07期

基金：

美国国家科学基金会;

关键词：

D O I：

10.1016/0968-0004(90)90047-F

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

Membrane proteins are found in a variety of conformations, with each protein spanning the membrane a set number of times and adopting a particular orientation. Positively charged residues, often located near the boundaries of transmembrane segments, appear to be involved in specifying the topology of membrane proteins. © 1990.

引用

页码：253 / 257

页数：5

共 36 条

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