FENFLURAMINE-INDUCED PLACE AVERSION IN A 3-CHOICE APPARATUS

被引：16

作者：

DAVIES, AM ^{[1
]}

PARKER, LA ^{[1
]}

机构：

[1] WILFRID LAURIER UNIV, DEPT PSYCHOL, WATERLOO N2L 3C5, ONTARIO, CANADA

来源：

PHARMACOLOGY BIOCHEMISTRY AND BEHAVIOR | 1993年 / 44卷 / 03期

关键词：

FENFLURAMINE; SEROTONIN; PLACE CONDITIONING; FEEDING; ANOREXIA;

D O I：

10.1016/0091-3057(93)90172-P

中图分类号：

B84 [心理学]; C [社会科学总论]; Q98 [人类学];

学科分类号：

03 ; 0303 ; 030303 ; 04 ; 0402 ;

摘要：

The hedonic properties of the anorectic agent fenfluramine (0.25, 1.0, 2.5, 5.0, and 10.0 mg/kg) were assessed in two experiments in a place conditioning paradigm. After four conditioning trials, rats were tested for their preference for a drug-paired chamber, saline-paired chamber, and a novel chamber. Fenfluramine produced a place aversion at doses of 2.5-10 mg/kg.

引用

页码：595 / 600

页数：6

共 38 条

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