CHEMOENZYMATIC SYNTHESIS OF 1-O-ACYL-3-O-(6'-O-ACYL-BETA-D-GALACTOPYRANOSYL)-SN-GLYCEROL

被引：17

作者：

MORIMOTO, T ^{[1
]}

NAGATSU, A ^{[1
]}

MURAKAMI, N ^{[1
]}

SAKAKIBARA, J ^{[1
]}

机构：

[1] NAGOYA CITY UNIV,FAC PHARMACEUT SCI,MIZUHO KU,NAGOYA,AICHI 467,JAPAN

来源：

TETRAHEDRON | 1995年 / 51卷 / 23期

关键词：

D O I：

10.1016/0040-4020(95)00299-N

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

Convenient synthesis of 1-O-acyl-3-O-(6'-O-acyl-beta-D-galactopyranosyl)-sn-glycerol was studied. The lipase from Achromobacter sp, catalyzed acylation of 3-O-beta-D-galactopyranosyl-sn-glycerol, which contains two primary hydroxyl functions, proceeded regioselectively to furnish 1-O-acyl-3-O-beta-D-galactopyranosyl-sn-glycerol.

引用

页码：6443 / 6450

页数：8

共 20 条

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