COMPARISON OF NEBULIZED AEROSOL DEPOSITION IN THE LUNGS OF HEALTHY-ADULTS FOLLOWING ORAL AND NASAL INHALATION

被引：71

作者：

EVERARD, ML ^{[1
]}

HARDY, JG ^{[1
]}

MILNER, AD ^{[1
]}

机构：

[1] QUEENS MED CTR,DEPT MED PHYS,NOTTINGHAM NG7 2UH,ENGLAND

来源：

THORAX | 1993年 / 48卷 / 10期

关键词：

D O I：

10.1136/thx.48.10.1045

中图分类号：

R56 [呼吸系及胸部疾病];

学科分类号：

摘要：

A standard jet nebuliser was used to generate a radiolabelled aerosol and the pattern of deposition within the airways of eight healthy adults was studied with a gamma camera. Penetration of aerosol to the lung was greatly reduced when breathing through the nose compared with mouth breathing.

引用

页码：1045 / 1046

页数：2

共 10 条

[1] Agnew J E, 1982, Clin Phys Physiol Meas, V3, P21, DOI 10.1088/0143-0815/3/1/002
[2] DRUG DELIVERY FROM JET NEBULIZERS
EVERARD, ML
CLARK, AR
MILNER, AD
[J]. ARCHIVES OF DISEASE IN CHILDHOOD, 1992, 67 (05) : 586 - 591
[3] HATCH TF, 1964, PULMONARY DEPOSITION, P45
[4] JOHNSON MA, 1989, CHEST, V96, P1
[5] DEPOSITION OF CARBENICILLIN AEROSOLS IN CYSTIC-FIBROSIS - EFFECTS OF NEBULIZER SYSTEM AND BREATHING PATTERN
NEWMAN, SP
WOODMAN, G
CLARKE, SW
[J]. THORAX, 1988, 43 (04) : 318 - 322
[6] DROPLET SIZE DISTRIBUTIONS OF NEBULIZED AEROSOLS FOR INHALATION-THERAPY
NEWMAN, SP
PELLOW, PGD
CLARKE, SW
[J]. CLINICAL PHYSICS AND PHYSIOLOGICAL MEASUREMENT, 1986, 7 (02): : 139 - 146
[7] NEWMAN SP, 1989, NEBULISER THERAPY SC, P2
[8] RUFFIN RE, 1978, CLIN PHARMACOL THER, V23, P338
[9] FACEMASK OR MOUTHPIECE FOR DELIVERY OF NEBULIZED BRONCHODILATOR AEROSOLS
STEVENTON, RD
WILSON, RSE
[J]. BRITISH JOURNAL OF DISEASES OF THE CHEST, 1981, 75 (01): : 88 - 90
[10] WOOD DO, 1978, AUST PAEDIATR J, V14, P150

← 1 →