ANTIPLATELET EFFECTS AND VASORELAXING ACTION OF SOME CONSTITUENTS OF FORMOSAN PLANTS

被引：54

作者：

CHUNG, MI ^{[1
]}

GAN, KH ^{[1
]}

LIN, CN ^{[1
]}

KO, FN ^{[1
]}

TENG, CM ^{[1
]}

机构：

[1] NATL TAIWAN UNIV,COLL MED,INST PHARMACOL,TAIPEI 100,TAIWAN

来源：

JOURNAL OF NATURAL PRODUCTS | 1993年 / 56卷 / 06期

关键词：

D O I：

10.1021/np50096a018

中图分类号：

Q94 [植物学];

学科分类号：

071001 ;

摘要：

Various xanthones as well as quercetin have been shown to exhibit antiplatelet activity. A series of anthraquinones analogues structurally related to xanthones and a series of quercetin-related compounds were tested for their antiplatelet effects Emodin, frangulin B, kaempferol tetraacetate, quercetin-3-O-galactoside octaacetate, rhamnazin triacetate, and rhamnetin tetraacetate were found to be potent antiplatelet agents, and 1,8-dihydroxy-6-3-methylanthraquinone 8-O-rhamnosyl-(1-->2)-glucoside, rhamnustrioside undecaacetate, rutin decaacetate, and quercetin-3-O-(6-O-alpha-L-arabinopyranosyl)-beta-D-galactopyranoside decaacetate showed significant antiplatelet effects. Quercetin showed vasorelaxing action in rat thoracic aorta.

引用

页码：929 / 934

页数：6

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