Fertility Preservation for Cancer Patients: A Review

被引:40
作者
Ajala, Tosin [1 ]
Rafi, Junaid [1 ]
Larsen-Disney, Peter [2 ,3 ]
Howell, Richard [2 ,3 ]
机构
[1] Basingstoke & North Hampshire NHS Trust, Dept Obstet & Gynaecol, Basingstoke RG24 9NA, Hants, England
[2] Brighton Univ Hosp, Dept Obstet & Gynaecol, Brighton BN2 5BE, E Sussex, England
[3] Sussex Univ Hosp, Dept Obstet & Gynaecol, Brighton BN2 5BE, E Sussex, England
关键词
D O I
10.1155/2010/160386
中图分类号
R71 [妇产科学];
学科分类号
100211 ;
摘要
Infertility can arise as a consequence of treatment of oncological conditions. The parallel and continued improvement in both the management of oncology and fertility cases in recent times has brought to the fore-front the potential for fertility preservation in patients being treated for cancer. Oncologists must be aware of situations where their treatment will affect fertility in patients who are being treated for cancer and they must also be aware of the pathways available for procedures such as cryopreservation of gametes and/or embryos. Improved cancer care associated with increased cure rates and long termsurvival, coupled with advances in fertility treatment means that it is now imperative that fertility preservation is considered as part of the care offered to these patients. This can only be approached within a multidisciplinary setting. There are obvious challenges that still remain to be resolved, especially in the area of fertility preservation in prepubertal patients. These include ethical issues, such as valid consent and research in the area of tissue retrieval, cryopreservation, and transplantation.
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页数:9
相关论文
共 64 条
[1]   PREDICTION OF LONG-TERM GONADAL TOXICITY AFTER STANDARD TREATMENT FOR TESTICULAR CANCER [J].
AASS, N ;
FOSSA, SD ;
THEODORSEN, L ;
NORMAN, N .
EUROPEAN JOURNAL OF CANCER, 1991, 27 (09) :1087-1091
[2]   Guidelines on testicular cancer [J].
Albers, P ;
Albrecht, W ;
Algaba, F ;
Bokemeyer, C ;
Cohn-Cedermark, G ;
Horwich, A ;
Klepp, O ;
Laguna, MP ;
Pizzocaro, G .
EUROPEAN UROLOGY, 2005, 48 (06) :885-894
[3]   THE SHORT-TERM AND LONG-TERM EFFECT OF A PREGNANCY ON BREAST-CANCER RISK - A PROSPECTIVE-STUDY OF 802,457 PAROUS NORWEGIAN WOMEN [J].
ALBREKTSEN, G ;
HEUCH, I ;
KVALE, G .
BRITISH JOURNAL OF CANCER, 1995, 72 (02) :480-484
[4]   Fertility preservation of boys undergoing anti-cancer therapy: a review of the existing situation and prospects for the future [J].
Aslam, I ;
Fishel, S ;
Moore, H ;
Dowell, K ;
Thornton, S .
HUMAN REPRODUCTION, 2000, 15 (10) :2154-2159
[5]   LUTEINIZING-HORMONE-RELEASING HORMONE AGONIST INHIBITS CYCLOPHOSPHAMIDE-INDUCED OVARIAN FOLLICULAR DEPLETION IN RHESUS-MONKEYS [J].
ATAYA, K ;
RAO, LV ;
LAWRENCE, E ;
KIMMEL, R .
BIOLOGY OF REPRODUCTION, 1995, 52 (02) :365-372
[6]   Pathophysiological effects of radiation on atherosclerosis development and progression, and the incidence of cardiovascular complications [J].
Basavaraju, SR ;
Easterly, CE .
MEDICAL PHYSICS, 2002, 29 (10) :2391-2403
[7]   Paternity following treatment for testicular cancer [J].
Brydoy, M ;
Fosså, SD ;
Klepp, O ;
Bremnes, RM ;
Wist, EA ;
Wentzel-Larsen, T ;
Dahl, O .
JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE, 2005, 97 (21) :1580-1588
[8]  
Budgell GJ, 2001, CLIN ONCOL-UK, V13, P120, DOI 10.1007/s001740170096
[9]  
Carlson R. H., 2009, ONCOLOGY TIMES, V32
[10]  
Critchley Hilary O D, 2005, J Natl Cancer Inst Monogr, P64