STRUCTURE OF A MOUSE HISTONE-ENCODING GENE-CLUSTER

被引：25

作者：

GRUBER, A

STREIT, A

REIST, M

BENNINGER, P

BOHNI, R

SCHUMPERLI, D

机构：

[1] UNIV BERN,INST ZOOL,ENTWICKLUNGSBIOL ABT,BALTZERSTR 4,CH-3012 BERN,SWITZERLAND

[2] UNIV ZURICH,INST MOLEK BIOL 2,CH-8093 ZURICH,SWITZERLAND

来源：

GENE | 1990年 / 95卷 / 02期

关键词：

gene family; nucleotide sequence; overlapping clones; promoter architecture; pseudogene; Recombinant DNA;

D O I：

10.1016/0378-1119(90)90377-4

中图分类号：

Q3 [遗传学];

学科分类号：

071007 ; 090102 ;

摘要：

In addition to a previously described histone (H)-encoding H4 gene [Meier et al., Nucleic Acids Res. 17 (1989) 795], the mouse genomic DNA clone 53 contains two H3 genes, one functional and one partially deleted H2A gene, and one H2B gene. Clone 53 overlaps for 3 kb with MH143, another previously isolated mouse H-encoding clone [Yang et al., J. Biol. Chem. 262 (1987) 17118-17125], thus defining a 32-kb region of mouse chromosome 13 with a total of seven H-encoding genes. We have determined the nucleotide sequences and transcription start points of two genes coding for the H2A.1 and H3.2 proteins. © 1990.

引用

页码：303 / 304

页数：2

共 8 条

[1] TRANSCRIPTION TERMINATION AND 3' PROCESSING - THE END IS IN SITE [J].