A MODIFICATION OF THE GENERAL STOCHASTIC EPIDEMIC MOTIVATED BY AIDS MODELING

被引:31
作者
BALL, F
ONEILL, P
机构
关键词
EPIDEMICS; SIZE OF EPIDEMIC; DETERMINISTIC AND STOCHASTIC MODELS; TIME-DEPENDENT SOLUTION; THRESHOLD THEOREMS; EMBEDDED RANDOM WALKS; VARIABILITY IN SUSCEPTIBILITY;
D O I
10.2307/1427495
中图分类号
O21 [概率论与数理统计]; C8 [统计学];
学科分类号
020208 ; 070103 ; 0714 ;
摘要
This paper considers a model for the spread of an epidemic in a closed, homogeneously mixing population in which new infections occur at rate betaxy/(x + y), where x and y are the numbers of susceptible and infectious individuals, respectively, and beta is an infection parameter. This contrasts with the standard general epidemic in which new infections occur at rate betaxy. Both the deterministic and stochastic versions of the modified epidemic are analysed. The deterministic model is completely soluble. The time-dependent solution of the stochastic model is derived and the total size distribution is considered. Threshold theorems, analogous to those of Whittle (1955) and Williams (1971) for the general stochastic epidemic, are proved for the stochastic model. Comparisons are made between the modified and general epidemics. The effect of introducing variability in susceptibility into the modified epidemic is studied.
引用
收藏
页码:39 / 62
页数:24
相关论文
共 28 条
[11]   STATISTICAL-ANALYSIS OF CHAIN-BINOMIAL EPIDEMIC MODELS WITH SEVERAL KINDS OF SUSCEPTIBLES [J].
GART, JJ .
BIOMETRICS, 1972, 28 (04) :921-930
[12]   MATHEMATICAL ANALYSIS OF AN EPIDEMIC WITH 2 KINDS OF SUSCEPTIBLES [J].
GART, JJ .
BIOMETRICS, 1968, 24 (03) :557-&
[13]   THE SPREAD OF EPIDEMICS [J].
GLEISSNER, W .
APPLIED MATHEMATICS AND COMPUTATION, 1988, 27 (02) :167-171
[14]   MATHEMATICAL-MODELING OF THE TRANSMISSION DYNAMICS OF HIV INFECTION AND AIDS - A REVIEW [J].
ISHAM, V .
JOURNAL OF THE ROYAL STATISTICAL SOCIETY SERIES A-STATISTICS IN SOCIETY, 1988, 151 :5-30
[15]  
ISHAM V, 1988, J ROYAL STAT SOC A, V151, P44
[16]   REPRODUCTION NUMBERS AND THRESHOLDS IN STOCHASTIC EPIDEMIC MODELS .1. HOMOGENEOUS POPULATIONS [J].
JACQUEZ, JA ;
ONEILL, P .
MATHEMATICAL BIOSCIENCES, 1991, 107 (02) :161-186
[17]   MODELING AND ANALYZING HIV TRANSMISSION - THE EFFECT OF CONTACT PATTERNS [J].
JACQUEZ, JA ;
SIMON, CP ;
KOOPMAN, J ;
SATTENSPIEL, L ;
PERRY, T .
MATHEMATICAL BIOSCIENCES, 1988, 92 (02) :119-199
[18]  
Kendall D.G., 1965, MATH COMPUTER SCI BI, P213
[19]  
KENDALL D. G., 1956, 3RD BERK S MATH STAT, VIV, P149
[20]   TRANSITION-PROBABILITIES OF GENERAL STOCHASTIC EPIDEMIC MODEL [J].
KRYSCIO, RJ .
JOURNAL OF APPLIED PROBABILITY, 1975, 12 (03) :415-424