VITAMIN-C INFLUENCE ON LOCALIZED ADJUVANT ARTHRITIS

被引:14
作者
DAVIS, RH
ROSENTHAL, KY
CESARIO, LR
ROUW, GR
机构
来源
JOURNAL OF THE AMERICAN PODIATRIC MEDICAL ASSOCIATION | 1990年 / 80卷 / 08期
关键词
D O I
10.7547/87507315-80-8-414
中图分类号
R826.8 [整形外科学]; R782.2 [口腔颌面部整形外科学]; R726.2 [小儿整形外科学]; R62 [整形外科学(修复外科学)];
学科分类号
摘要
This work attempts to determine the influence of vitamin C on locally induced inflammation and arthritis in rat paws, as measured by rat paw swelling, polymorphonuclear leukocyte infiltration, pain, and surface skin temperature. Daily subcutaneous administration of 150 mg/kg of vitamin C over 20 days reduced arthritic swelling, increased pain tolerance, and decreased polymorphonuclear leukocyte infiltration, with no significant change in surface temperature. Vitamin C may provide podiatrists with a supplemental or alternative treatment for patients with rheumatoid arthritis.
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页码:414 / 418
页数:5
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