SHORT SEQUENCE IN L1 REGION OF HUMAN PAPILLOMAVIRUSES CORRELATES WITH CLINICAL PICTURES AND GROUPING BY CROSS-HYBRIDIZATION

被引：11

作者：

IWAMOTO, A

YOSHIKAWA, H

KITAGAWA, K

IGARASHI, H

KAWANA, T

YOSHIKURA, H

机构：

[1] UNIV TOKYO,FAC MED,DEPT OBSTET & GYNECOL,BUNKYO KU,TOKYO 113,JAPAN

[2] TOKYO UNIV BRANCH HOSP,DEPT OBSTET & GYNECOL,BUNKYO KU,TOKYO 112,JAPAN

来源：

JAPANESE JOURNAL OF CANCER RESEARCH | 1992年 / 83卷 / 04期

关键词：

HUMAN PAPILLOMAVIRUS; CERVICAL CARCINOMA; POLYMERASE CHAIN REACTION;

D O I：

10.1111/j.1349-7006.1992.tb00107.x

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

A consensus primer-mediated polymerase chain reaction devised to amplify a short sequence in L1 region (L1-PCR) efficiently detected genital human papillomaviruses (HPVs) in clinical materials. Nucleotide sequencing of the amplified fragment showed that L1-PCR is also applicable to hitherto unsequenced HPVs. By comparing the amplified 210 nucleotides HPVs were classified into six groups, which are consistent with clinical pictures and a grouping based on cross-hybridization under the stringent condition.

引用

收藏

页码：315 / 319

页数：5

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