PRODUCTION OF THE POSITRON EMITTING RADIOISOTOPE-Y-86 FOR NUCLEAR MEDICAL APPLICATION

被引：91

作者：

ROSCH, F

QAIM, SM

STOCKLIN, G

机构：

[1] Institut für Nuklearchemie, Forschungszentrum Jülich GmbH

来源：

APPLIED RADIATION AND ISOTOPES | 1993年 / 44卷 / 04期

关键词：

D O I：

10.1016/0969-8043(93)90131-S

中图分类号：

O61 [无机化学];

学科分类号：

070301 ; 081704 ;

摘要：

The production of Y-86 via the Sr-86(p,n)-reaction was studied. Samples of 96.3% enriched (SrCO3)-Sr-86 were irradiated using a 4 pi water-cooled target system at nearly optimum proton energy ranges (14 --> 10 MeV) at beam currents of 3-8 muA. Thick target yields calculated from the measured excitation functions were compared with results from production runs. A chemical separation procedure including the recovery of the enriched target material was developed. Activities of about 1.5 GBq (40 mCi) Y-86 per batch with high radionuclidic and radiochemical purity were achieved and [Y-86]citrate was prepared for pharmacokinetic studies using PET.

引用

页码：677 / 681

页数：5

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