OPTICAL RESOLUTION BY ELECTROKINETIC CHROMATOGRAPHY USING OVOMUCOID AS A PSEUDO-STATIONARY PHASE

被引：58

作者：

ISHIHAMA, Y

ODA, Y

ASAKAWA, N

YOSHIDA, Y

SATO, T

机构：

[1] Department of Physical and Analytical Chemistry, Tsukuba Research Laboratories, Eisai Co., Ltd., Tsukuba, Ibaraki, 300-26

来源：

JOURNAL OF CHROMATOGRAPHY A | 1994年 / 666卷 / 1-2期

关键词：

D O I：

10.1016/0021-9673(94)80381-1

中图分类号：

Q5 [生物化学];

学科分类号：

071010 ; 081704 ;

摘要：

The utilization of ovomucoid as a chiral pseudo-stationary phase in electrokinetic chromatography was studied. Optical resolution of some drugs was achieved successfully with high efficiency by optimizing the concentrations of both ovomucoid and an organic solvent. The reproducibility was improved by the addition of cellulose derivatives to the separation solutions or by using coated capillaries. This approach is expected to have wide applications.

引用

页码：193 / 201

页数：9

共 34 条

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