INVIVO ENHANCEMENT OF NK-CELL ACTIVITY BY THYMOPENTIN

被引：13

作者：

HU, C

RADELLI, L

SCORZA, R

BONARA, P

PEREGO, R

FANTUZZI, G

机构：

[1] ITALFARMACO SPA,DEPT MED,MILAN,ITALY

[2] UNIV MILAN,INST INTERNAL MED INFECT DIS & IMMUNOPATHOL,I-20122 MILAN,ITALY

来源：

INTERNATIONAL JOURNAL OF IMMUNOPHARMACOLOGY | 1990年 / 12卷 / 02期

关键词：

D O I：

10.1016/0192-0561(90)90053-P

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Natural killer (NK) activities of fresh and IL-2-precultured peripheral blood mononuclear cells (PBMC) were investigated in 13 elderly subjects before and after thymopentin (TP-5) treatment and in 12 age-matched controls. The NK activity of fresh PBMC was found to be significantly higher in subjects given TP-5 at 50 mg s.c. three times per week for one month. Conversely, this type of treatment with TP-5 did not significantly modifie the cytotoxic capacity of IL-2-precultured PBMC. © 1990.

引用

页码：193 / 197

页数：5

共 20 条

[1]

BOYUM A, 1968, SCAND J CLIN LAB INV, VS 21, P77

[2]

CHISESI T, 1988, J BIOL REG HOMEOS AG, V2, P193

[3]

DEMPSEY RA, 1982, J IMMUNOL, V129, P2504

[4]

DOMZIG W, 1983, J IMMUNOL, V130, P1970