DIHYDROMONACOLIN-L AND MONACOLIN-X, NEW METABOLITES THOSE INHIBIT CHOLESTEROL-BIOSYNTHESIS

被引：75

作者：

ENDO, A ^{[1
]}

HASUMI, K ^{[1
]}

NAKAMURA, T ^{[1
]}

KUNISHIMA, M ^{[1
]}

MASUDA, M ^{[1
]}

机构：

[1] NIPPON KAYAKU CO LTD,DIV PHARMACEUT,RES LABS,KITA KU,TOKYO 115,JAPAN

来源：

JOURNAL OF ANTIBIOTICS | 1985年 / 38卷 / 03期

关键词：

D O I：

10.7164/antibiotics.38.321

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

引用

页码：321 / 327

页数：7

共 10 条

[1] DIHYDROMEVINOLIN, A POTENT HYPOCHOLESTEROLEMIC METABOLITE PRODUCED BY ASPERGILLUS-TERREUS
ALBERSSCHONBERG, G
JOSHUA, H
LOPEZ, MB
HENSENS, OD
SPRINGER, JP
CHEN, J
OSTROVE, S
HOFFMAN, CH
ALBERTS, AW
PATCHETT, AA
[J]. JOURNAL OF ANTIBIOTICS, 1981, 34 (05) : 507 - 512
[2] MEVINOLIN - A HIGHLY POTENT COMPETITIVE INHIBITOR OF HYDROXYMETHYLGLUTARYL-COENZYME-A REDUCTASE AND A CHOLESTEROL-LOWERING AGENT
ALBERTS, AW
CHEN, J
KURON, G
HUNT, V
HUFF, J
HOFFMAN, C
ROTHROCK, J
LOPEZ, M
JOSHUA, H
HARRIS, E
PATCHETT, A
MONAGHAN, R
CURRIE, S
STAPLEY, E
ALBERSSCHONBERG, G
HENSENS, O
HIRSHFIELD, J
HOOGSTEEN, K
LIESCH, J
SPRINGER, J
[J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA-BIOLOGICAL SCIENCES, 1980, 77 (07): : 3957 - 3961
[3] COMPETITIVE INHIBITION OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME A REDUCTASE BY ML-236A AND ML-236B FUNGAL METABOLITES, HAVING HYPOCHOLESTEROLEMIC ACTIVITY
ENDO, A
KURODA, M
TANZAWA, K
[J]. FEBS LETTERS, 1976, 72 (02) : 323 - 326
[4] MONACOLIN-J AND MONACOLIN-L NEW INHIBITORS OF CHOLESTEROL-BIOSYNTHESIS PRODUCED BY MONASCUS-RUBER
ENDO, A
HASUMI, K
NEGISHI, S
[J]. JOURNAL OF ANTIBIOTICS, 1985, 38 (03) : 420 - 422
[5] BIOLOGICAL AND PHARMACOLOGICAL ACTIVITY OF INHIBITORS OF 3-HYDROXY-3-METHYLGLUTARYL COENZYME-A REDUCTASE
ENDO, A
[J]. TRENDS IN BIOCHEMICAL SCIENCES, 1981, 6 (01) : 10 - 13
[6] MONACOLIN-K, A NEW HYPOCHOLESTEROLEMIC AGENT PRODUCED BY A MONASCUS SPECIES
ENDO, A
[J]. JOURNAL OF ANTIBIOTICS, 1979, 32 (08) : 852 - 854
[7] ML-236A, ML-236B, AND ML-236C, NEW INHIBITORS OF CHOLESTEROGENESIS PRODUCED BY PENICILLIUM CITRINUM
ENDO, A
KURODA, M
TSUJITA, Y
[J]. JOURNAL OF ANTIBIOTICS, 1976, 29 (12) : 1346 - 1348
[8] ENDO A, 1984, REGULATION HMG COA R
[9] KURODA M, 1977, BIOCHIM BIOPHYS ACTA, V486, P70
[10] LAM TYK, 1981, J ANTIBIOT, V34, P614

← 1 →