AROMATIC CYCLIZATIONS OF BETA-AMINOETHYL RADICALS AND ALPHA-CARBAMOYLMETHYL RADICALS - ORTHO-SUBSTITUTION VS IPSO-SUBSTITUTION

被引：35

作者：

ISHIBASHI, H

NAKAMURA, N

ITO, K

KITAYAMA, S

IKEDA, M

机构：

[1] Kyoto Pharmaceutical University, Kyoto, 607, Misasagi, Yamashina

来源：

HETEROCYCLES | 1990年 / 31卷 / 10期

关键词：

D O I：

10.3987/COM-90-5559

中图分类号：

O62 [有机化学];

学科分类号：

070303 ; 081704 ;

摘要：

On being treated with Bu3SnH, the N-benzyl-N-(β-bromoethyl) sulfonamide (4) underwent a homolytic ortho-substitution reaction to give the tetrahydroisoquinoline (6). In contrast, the N-arylmethyl α-chloroacetamides (10) afforded the ipso-substitution products (11). A similar treatment of the N-naphthylmethyl derivative (16) provided the spiro-γ-lactam (17). © 1990.

引用

页码：1781 / 1784

页数：4

共 16 条

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