CHEMISTRY OF POTENTIALLY PREBIOLOGICAL NATURAL-PRODUCTS

被引:198
作者
ESCHENMOSER, A [1 ]
LOEWENTHAL, E [1 ]
机构
[1] TECHNION ISRAEL INST TECHNOL, DEPT CHEM, IL-32000 HAIFA, ISRAEL
关键词
D O I
10.1039/cs9922100001
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
The demonstration that biologically relevant molecules can be generated non-enzymically from precursors as simple as hydrogen cyanide, and found in interstellar space, identifies possible pathways for the molecular mechanisms of the origin of life. The reason why Nature uses pentoses in nucleic acids and not hexoses can be understood by comparing the properties of 'homo-DNA' oligonucleotides derived from e.g. 2',3-dideoxyallose with those of DNA oligonucleotides from deoxyribose.
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页码:1 / 16
页数:16
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