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Detection by Western blot of four antigens characterizing acute clinical leishmaniasis due to Leishmania infantum
被引:52
作者:
Marty, P
Lelievre, A
Quaranta, JF
Suffia, I
Eulalio, M
GariToussaint, M
LeFichoux, Y
Kubar, J
机构:
[1] Groupe de Recherche en Immunopathologie de la Leishmaniose, Université de Nice–Sophia Antipolis, Nice Cedex, 06107, Avenue de Valombrose
关键词:
leishmaniasis;
Leishmania infantum;
characteristic antigens;
France;
D O I:
10.1016/0035-9203(95)90447-6
中图分类号:
R1 [预防医学、卫生学];
学科分类号:
1004 ;
120402 ;
摘要:
Western blot analysis of sera from 32 patients with acute clinical leishmaniasis due to Leishmania infantum showed the simultaneous presence of antibodies against 4 antigens with molecular masses of 18, 21, 23, 31 kDa. The simultaneous presence of these 4 antigens was specific to the clinical disease and it was not detected in 47 sera from asymptomatic individuals living in the leishmaniasis endemic area of Alpes-Maritimes (southern France) or in 37 sera from patients with other protozoan infections.
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页码:690 / 691
页数:2
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