PHENOBARBITAL-INDUCED PROLONGATION OF HALF-LIFE AND ALTERATION OF DISTRIBUTION OF A PHENOTHIAZINE DRUG METABOLITE IN RAT

被引：8

作者：

BREYER, U ^{[1
]}

JUNGINGER, W ^{[1
]}

VILLUMSEN, D ^{[1
]}

机构：

[1] UNIV TUBINGEN,INST TOXICOL,D-7400 TUBINGEN 1,FED REP GER

来源：

BIOCHEMICAL PHARMACOLOGY | 1976年 / 25卷 / 23期

关键词：

D O I：

10.1016/0006-2952(76)90518-9

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

引用

页码：2623 / 2629

页数：7

共 29 条

[1] DECREASE IN SERUM DIPHENYLHYDANTOIN LEVELS AFTER WITHDRAWAL OF PHENOBARBITAL IN EPILEPTICS TREATED WITH BOTH DRUGS [J].

ARAKAWA, T ;

YOSHIDA, T ;

TANABU, M ;

KARAHASHI, M ;

TAKAGI, T .

TOHOKU JOURNAL OF EXPERIMENTAL MEDICINE, 1974, 112 (02) :165-168

[2] DRUG-METABOLIZING CAPACITY IN STATES OF DRUG DEPENDENCE AND WITHDRAWAL [J].

BALLINGE.B ;

BROWNING, M ;

STEVENSO.IH .

BRITISH JOURNAL OF PHARMACOLOGY, 1972, 45 (04) :638-&

[3] TISSUE METABOLITES OF TRIFLUOPERAZINE, FLUPHENAZINE, PROCHLORPERAZINE, AND PERPHENAZINE IN RAT - IDENTIFICATION AND SYNTHESIS [J].

BREYER, U ;

PROX, A ;

BERTELE, R ;

GAERTNER, HJ .

JOURNAL OF PHARMACEUTICAL SCIENCES, 1974, 63 (12) :1842-1848

[4]

BREYER U, 1973, N-S ARCH PHARMACOL, V279, pR32

[5] ACCUMULATION AND ELIMINATION OF A NOVEL METABOLITE DURING CHRONIC ADMINISTRATION OF PHENOTHIAZINE DRUG PERAZINE TO RATS [J].

BREYER, U .

BIOCHEMICAL PHARMACOLOGY, 1972, 21 (10) :1419-&

[6] CUMULATING METABOLITE DERIVED FROM A PIPERAZINE-SUBSTITUTED PHENOTHIAZINE DRUG [J].

BREYER, U ;

KRAUSS, D ;

JOCHIMS, JC .

EXPERIENTIA, 1972, 28 (03) :312-&

[7] MEASUREMENT OF PLASMA-LEVELS OF TRICYCLIC PSYCHOACTIVE-DRUGS AND THEIR METABOLITES BY UV REFLECTANCE PHOTOMETRY OF THIN-LAYER CHROMATOGRAMS [J].

BREYER, U ;

VILLUMSEN, K .

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 1976, 9 (5-6) :457-465

[8] FORMATION OF IDENTICAL METABOLITES FROM PIPERAZINE-SUBSTITUTED AND DIMETHYLAMINO-SUBSTITUTED PHENOTHIAZINE DRUGS IN MAN, RAT AND DOG [J].

BREYER, U ;

GAERTNER, HJ ;

PROX, A .

BIOCHEMICAL PHARMACOLOGY, 1974, 23 (02) :313-322

[9]

BREYER U, 1973, EXCERPTA MED 288, P59

[10]

CONNEY AH, 1960, J PHARMACOL EXP THER, V130, P1

← 1 2 3 →