MULTIDRUG RESISTANCE AND ELECTROMAGNETIC-FIELDS

被引：9

作者：

PETRINI, M

MATTII, L

SABBATINI, A

CARULLI, G

GRASSI, B

CADOSSI, R

RONCA, G

CONTE, A

机构：

[1] UNIV MODENA,MED CLIN,I-41100 MODENA,ITALY

[2] UNIV PISA,IST BIOQUIM,I-56100 PISA,ITALY

来源：

JOURNAL OF BIOELECTRICITY | 1990年 / 9卷 / 02期

关键词：

D O I：

10.3109/15368379009119809

中图分类号：

Q6 [生物物理学];

学科分类号：

071011 ;

摘要：

The effect of low-frequency electromagnetic fields (EMFs) on the multidrug resistant cell line MCF7 dx was studied. In cultures containing 40 mg/ml doxorubicin, incorporation of H-3-thymidine was inhibited by exposure to EMFs. The effect may have occurred via functional inhibition of P-glycoprotein.

引用

收藏

页码：209 / 212

页数：4

相关论文

共 12 条

[1] SENSITIVITY OF CALCIUM-BINDING IN CEREBRAL TISSUE TO WEAK ENVIRONMENTAL ELECTRIC-FIELDS OSCILLATING AT LOW-FREQUENCY [J].

BAWIN, SM ;

ADEY, WR .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1976, 73 (06) :1999-2003

[2] INTERNAL DUPLICATION AND HOMOLOGY WITH BACTERIAL TRANSPORT PROTEINS IN THE MDR1 (P-GLYCOPROTEIN) GENE FROM MULTIDRUG-RESISTANT HUMAN-CELLS [J].

CHEN, CJ ;

CHIN, JE ;

UEDA, K ;

CLARK, DP ;

PASTAN, I ;

GOTTESMAN, MM ;

RONINSON, IB .

CELL, 1986, 47 (03) :381-389

[3] INTERACTION BETWEEN ELECTROMAGNETIC-FIELDS AND CELLS - MICROELECTROPHORETIC EFFECT ON LIGANDS AND SURFACE-RECEPTORS [J].

CHIABRERA, A ;

GRATTAROLA, M ;

VIVIANI, R .

BIOELECTROMAGNETICS, 1984, 5 (02) :173-191

[4] EXTREMELY LOW-FREQUENCY PULSED ELECTROMAGNETIC-FIELDS INCREASE CELL-PROLIFERATION IN LYMPHOCYTES FROM YOUNG AND AGED SUBJECTS [J].

COSSARIZZA, A ;

MONTI, D ;

BERSANI, F ;

CANTINI, M ;

CADOSSI, R ;

SACCHI, A ;

FRANCESCHI, C .

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS, 1989, 160 (02) :692-698

[5]

HAMADA H, 1988, J BIOL CHEM, V263, P1454

[6] ATP-DEPENDENT TRANSPORT OF VINBLASTINE IN VESICLES FROM HUMAN MULTIDRUG-RESISTANT CELLS [J].

HORIO, M ;

GOTTESMAN, MM ;

PASTAN, I .

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1988, 85 (10) :3580-3584

[7] CELL-SURFACE P-GLYCOPROTEIN ASSOCIATED WITH MULTIDRUG RESISTANCE IN MAMMALIAN-CELL LINES [J].

KARTNER, N ;

RIORDAN, JR ;

LING, V .

SCIENCE, 1983, 221 (4617) :1285-1288

[8] MAGNETIC FIELD-INDUCED DRUG PERMEABILITY IN LIPOSOME VESICLES [J].

LIBURDY, RP ;

TENFORDE, TS ;

MAGIN, RL .

RADIATION RESEARCH, 1986, 108 (01) :102-111

[9] REDUCED PERMEABILITY IN CHO-CELLS AS A MECHANISM OF RESISTANCE TO COLCHICINE [J].

LING, V ;

THOMPSON, LH .

JOURNAL OF CELLULAR PHYSIOLOGY, 1974, 83 (01) :103-116

[10]

PASTAN I, 1987, NEW ENGL J MED, V316, P1388