VACCINOPROPHYLAXIS OF MUMPS USING MUMPS VACCINE, STRAIN-SOFIA-6, IN BULGARIA

被引：11

作者：

ODISSEEV, H

GACHEVA, N

机构：

[1] CTR INFECT & PARASIT DIS,DEPT VIROL,BU-1000 SOFIA,BULGARIA

[2] CTR INFECT & PARASIT DIS,DEPT EPIDEMIOL,BU-1000 SOFIA,BULGARIA

来源：

VACCINE | 1994年 / 12卷 / 14期

关键词：

MUMPS VACCINE; STRAIN SOFIA 6; VACCINATION; REVACCINATION; SIDE-EFFECTS;

D O I：

10.1016/S0264-410X(94)80047-4

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

A mumps vaccine, using strain Sofia 6 prepared in guinea-pig kidney primary cell cultures, was gradually introduced in Bulgaria to vaccinate 1- to 12-year-old children between 1972 and 1976. It was included in the national vaccine programme in 1977. The vaccine showed a slight reactogenicity, a good immunogenicity and a high epidemiological efficacy. Due to the increased morbidity of mumps, revaccination was carried out in 4- to 12-year-old children in 1982. A high level of side-effects, mainly meningitis, was registered, and fed to suspension of the mumps vaccine in Bulgaria.

引用

页码：1251 / 1254

页数：4

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