THE 1984 TASMANIAN INSULIN-TREATED DIABETES-MELLITUS PREVALENCE COHORT - AN 8 AND A HALF YEAR MORTALITY FOLLOW-UP INVESTIGATION

被引：12

作者：

RILEY, MD ^{[1
]}

MCCARTY, DJ ^{[1
]}

COUPER, DJ ^{[1
]}

HUMPHREY, ARG ^{[1
]}

DWYER, T ^{[1
]}

ZIMMET, PZ ^{[1
]}

机构：

[1] INT DIABET INST, MELBOURNE, VIC, AUSTRALIA

来源：

DIABETES RESEARCH AND CLINICAL PRACTICE | 1995年 / 29卷 / 01期

关键词：

IDDM; NIDDM; MORTALITY; EPIDEMIOLOGY;

D O I：

10.1016/0168-8227(95)01106-N

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Total mortality and underlying cause of death were examined in a population-based prevalence cohort (n = 1232) of Tasmanians with insulin-treated diabetes mellitus. Eight and a half years after the establishment of the registry, the cause of death based on death certificate information was determined for the overall cohort and for three classification groups of insulin-treated diabetes: Group A - childhood-onset IDDM cases; Group B - adult-onset IDDM cases; and Group C - adult-onset insulin-treated NIDDM cases. A total of 378 deaths occurred, providing an overall SMR of 2.2 (95% CI 2.0-2.4) compared to the Tasmanian population. Diabetic females experienced a higher SMR (2.6, 95% CI 2.3-3.0) than diabetic males (1.9, 95% CI 1.6-2.2), The all-cause SMRs for the diabetic classification groups were 4.6 (95% CI 3.4-6.1) in Group A, 1.8 (95% CI 1.5-2.1) in Group B, and 2.2 (95% CI 1.9-2.6) in Group C. After adjusting for age, gender and duration of diabetes, the mortality in Group C was significantly higher compared to Group B (odds ratio 1.6, 95% CI 1.2-2.3), This study indicates that people with childhood-onset IDDM experience 4.6 times the death rate compared to the Tasmanian population and that the excess mortality is most pronounced in females.

引用

页码：27 / 35

页数：9

共 29 条

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