SYSTEMIC BONE-GROWTH FACTORS IN LIGHT BREED MARES AND THEIR FOALS

被引：20

作者：

DAVICCO, MJ ^{[1
]}

FAULCONNIER, Y ^{[1
]}

COXAM, V ^{[1
]}

DUBROEUCQ, H ^{[1
]}

MARTINROSSET, W ^{[1
]}

BARLET, JP ^{[1
]}

机构：

[1] INRA CLERMONT THEIX, ST GENES CHAMPANE, FRANCE

来源：

ARCHIVES INTERNATIONALES DE PHYSIOLOGIE DE BIOCHIMIE ET DE BIOPHYSIQUE | 1994年 / 102卷 / 02期

关键词：

GH; IGF-1; OSTEOCALCIN; CALCIUM; MARES; FOALS;

D O I：

10.3109/13813459408996117

中图分类号：

Q5 [生物化学]; Q7 [分子生物学];

学科分类号：

071010 ; 081704 ;

摘要：

There is a high incidence of bony pathology in race horses. Thus, plasma GH, IGF-1, osteocalcin (OC), calcium (Ca) and inorganic phosphorus (P) concentrations were measured in 12 healthy Selle Francais foals and their dams during the first five months after birth. Plasma IGF-1 and OC concentrations were higher in foals than in mares (336 +/- 25 vs 230 +/- 18 ng/ml, P < 0.05; 52.5 +/- 3.2 vs 4.9 +/- 0.1 ng/mg, P < 0.01, respectively). A significant positive linear relationship could be established between these two parameters in foals (IGF-1 = 19 + 0.619 OC; P < 0.05). Another striking evidence was the increase in plasma IGF-1, OC and P concentrations observed during the first week of postnatal life. IGF-1, OC, P and Ca concentrations remained elevated during the experimental period, indicating an intense skeletal growth (confirmed by growth curve) in these animals.

引用

页码：115 / 119

页数：5

共 45 条

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